Senior Research Associate, Angiogenesis
We are an ambitious, growing startup seeking top performers with infectious enthusiasm, passion, and conviction who will be as committed to our core values and mission as we are. Because we're small, the pace is fast and our attitude is hands-on. We juggle a lot and do less with more and we love it. We have an exceptionally bright team brimming with cutting edge ideas and curiosity who thrive on collaboration so be ready to share you knowledge and prepare for continuous learning. The spirit of Abpro is entrepreneurial so you need to be proactive, autonomous, and solution-oriented to keep up. We value our diversity and believe that every individual counts and every idea matters so prepare to speak up and be heard.
Our Values - Accountability, Collaboration, Integrity, Excellence, Innovation
Abpro believes that a healthy company sets the stage, ultimately, for healthy patients. We pride ourselves on our five values and model them in all that we do.
This individual would be joining our Angiogenesis team, focusing on preclinical studies of ABP-201. ABP-201 is a next-generation bispecific antibody that targets both VEGF and Angiopoetin-2, or ANG-2. We are preparing to initiate clinical trials of ABP-201 in patients with diabetic macular edema in the second half of 2019. The successful candidate will work with the ABP-201 research team to fully characterize the molecule and evaluate its biological activity in various animal models of eye disease, as well as explore potential applications in cancer. Working independently, the candidate will be expected to design and perform experiments, organize and analyze results, and communicate and present findings in team meetings.
How You'll Contribute
Culturing cells and performing standard, cell-based assays
Performing standard in vitro assays such as ELISAs and Western blots
Performing standard molecular biology techniques (DNA manipulation)
Performing immunohistochemistry (IHC) assays including tissue processing, embedding, sectioning, and staining
Performing animal (rodent) studies including handling, dosing, and blood and tissue collection
Analyzing and communicating data
Maintaining thorough, accurate records of experiments
Keys to Success
Bachelor's Degree with at least 4 years of relevant lab experience (more experience preferred) - OR-
Master's Degree with at least 2 years of relevant lab experience (more experience preferred)
Experience in academic or biotech/pharma industry
Experience with animal handling and rodent models (experience with models of eye disease preferred)
Experience with histology and microscopy
Proficient in cellular and molecular biology techniques, including transfection, flow cytometry, plasmid manipulation, PCR, and Western blotting
Proficient in cell culture aseptic technique
Successful Candidate's Profile
Strong desire to learn
Strong written and verbal communication skills
Able to effectively communicate results to a diverse cross-functional audience
What's In It For You?
Abpro is growing quickly and opportunity abounds. We offer an environment where you'll be exposed to multiple initiatives at once and have a direct impact on helping to further our mission. Do you want to be part of the solution? Do you want to work with world-class scientists on the leading edge of medical breakthroughs? We are committed to work-life balance and, in addition to sick time, we offer 3 weeks vacation, flexible hours, and a Monthly Time Away From Work program. We also want you to be comfortable so you can concentrate on the science - dress is casual. We're all equals - our floor plan is completely open to promote collaboration and communication and there's a defined growth path for everyone. We offer a comprehensive Total Rewards compensation package including annual bonus, equity, and competitive base salary in addition to medical, dental, vision, LTD, STD, Life, and AD&D.
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